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Product Details
Liothyronine,Liothyronine
Liothyronine sodium
Liothyronine,Liothyronine sodium,T3(CAS:55-06-1)treat hypothyroidism and myxedema coma

Name

Liothyronine sodium(T3 or Liothyronine)

CAS

55-06-1

Synonyms

(S)-2-AMINO-3-[4-(4-HYDROXY-3-IODOPHENOXY)-3,5-DIIODOPHENYL]PROPIONIC ACID SODIUM SALT;SODIUM (S)-2-AMINO-3-[4-(4-HYDROXY-3-IODOPHENOXY)-3,5-DIIODOPHENYL]PROPIONATE;T3 SODIUM SALT;T3, NA;O-[4-HYDROXY-3-IODOPHENYL]-3,5-DIIODO-L-TYROSINE SODIUM SALT;LIOTHYR

MF

C15H11I3NNaO4

MW

672.96

Others

Physicians can use this instead of or in addition to levothyroxine (T4) for patients undergoing thyroid withdrawal. When a patient has thyroid cancer or Graves' disease, ablation therapy with radioactive iodine (131I) can be used to remove any trace thyroid tissue. For 131I therapy to be effective, the trace thyroid tissue must be avid to iodine. The best method is to starve the tissue of iodine but this can lead to hypothyroid symptoms for the patient. Withdrawal from levothyroxine can be done but it takes six weeks of withdrawal for the remaining thyroid tissue to be completely starved. Six weeks is needed owing to levothyroxine's long half life. Six weeks can be inconvenient for the patient and delay treatment. Liothyronine instead can be taken and withdrawn from for two weeks to starve the thyroid tissue. This is much safer and more convenient than levothyroxine. Also, due to its quicker onset of action when compared to levothyroxine, it sometimes is a better option in patients with myxedema coma or in patients preparing for 133I therapy for thyroid cancer.[1]